- "Foot soldiers of the Disciples of Seraph. Weak attackers hidden in the back line. Take them down!"
— Combat Description
The First Defense is a combat that can appear in Ring 1. It is the only Ring 1 combat to feature a Disciple Protector.
Like all non-boss combats, a Collector will appear on a random floor on wave 2.
| Wave | Enemies (Cov 0-4) | Enemies (Cov 5-25) |
|---|---|---|
| 1 | Disciple Protector | Discipled Footsoldier | Disciple Protector | Discipled Footsoldier |
| 2 | Forged Disciple | Discipled Footsoldier | Forged Disciple | Discipled Footsoldier | Discipled Footsoldier |
| 3 | A Brief Respite | A Brief Respite |
| 4 | BOSS | Discipled Footsoldier | BOSS | Discipled Footsoldier |
The Ring 1 Boss can be either Discipled Inquisitor or Chains the Sighted, regardless of the combat.
| Combats |
|---|
| Ring 1 |
| The First Defense | Heaven's Priests | The Gathered Clergy | Guardians of Light |
| Ring 2 |
| Disciple Conduits | Pyre Absorbers | Barbed Disciples | Penitent Prayers |
| Ring 3 |
| Daedalus, the Professor: Explosive Sigil | Double Barrel | Plating Seal Talos, the Architect: Empowering Offense | Soul Sucker | Protective Sin |
| Ring 4 |
| Clipped Infiltration | Protectors of the Clipped | Clipped Guard | Clipped Tormenters |
| Ring 5 |
| The Sycophants of Seraph | The Harpy's Guard | Hidden Assault | Harvesters of Death |
| Ring 6 |
| Fel, the Wings of Light: Eternal Crest | Scouring Crest | Wrath Crest Archus, Darkness Incarnate: Sin of Darkness | Sin of Shadow | Sin of Failure |
| Ring 7 |
| The Pyrewings | The Winged Horde | The Penitent | Conduit Masters | The Shadewings |
| Ring 8 |
| Seraph the Temperant | Seraph the Chaste | Seraph the Diligent | Seraph the Patient |
| Ring 9 |
| The Last Divinity: Divine Intervention |